Naloxone Methadone Combination (NAMEKO)

Summary

The aim of the study is to examine the tolerability and abuse potential of the diluted methadone solution (5 mg/ml → 2 mg/ml) in combination with naloxone in opioid substitution treatment. Study hypothesis: Treatment with this diluted combination product is safer than with methadone alone (5 mg/ml) and combination product does not precipitate withdrawal symptoms in opioid dependent patients.

Timeline

Start

2013-05

Primary completion

2013-07

Completion

2013-07

Drugs

Indications