drugset

drugset / Trial / NCT01160978

Donor Simvastatin Treatment in Organ Transplantation

NCT01160978 ↗

Phase 2/3 Completed 84 enrolled Helsinki University Central Hospital Academy of Finland · collab University of Helsinki · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The aim of the study is to investigate the effects of donor simvastatin treatment on ischemia-reperfusion injury after heart transplantation.

Timeline

Start: 2010-06-01
Primary completion: 2016-08-01
Completion: 2016-08-01

Publications

Nykanen AI, Holmstrom EJ, Tuuminen R, Krebs R, Dhaygude K, Kankainen M, Jokinen JJ, Lommi J, Helantera I, Raisanen-Sokolowski A, Syrjala SO, Lemstrom KB. Donor Simvastatin Treatment in Heart Transplantation. Circulation. 2019 Aug 20;140(8):627-640. doi: 10.1161/CIRCULATIONAHA.119.039932. Epub 2019 Jul 29.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Simvastatin	Small molecule	80 mg	Other

Indications