drugset / Trial / NCT01161277
Effects of Aripiprazole and Haloperidol on Mesolimbic System Functioning
RandomizedParallel-groupSingle-blindBasic science
Summary
The main objective is to investigate if the brain activation signature of a typical antipsychotic agent is dissociable from a newer drug with a pharmacological profile that differs from both typical and atypical antipsychotics since it is a potent partial D2 agonist. The method used to study this will be functional magnetic resonance imaging (fMRI).
Timeline
- Start
- 2010-08
- Primary completion
- 2011-06
- Completion
- 2011-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aripiprazole | Other / unclassified | 5 mg | — |
| Comparator | Aripiprazole | Other / unclassified | 10 mg | — |
| Comparator | Haloperidol | Other / unclassified | 1 mg | — |
| Comparator | Haloperidol | Other / unclassified | 2 mg | — |