drugset / Trial / NCT01163604

Argatroban for Preventing Occlusion and Restenosis After Intracranial and Extracranial Artery Stenting

NCT01163604

Phase 4 Completed 114 enrolled Jinling Hospital, China
RandomizedParallel-groupOpen-labelTreatment

Summary

Argatroban is a selective thrombin inhibitor, and previous study had suggested that argatroban use post PCI could potentially prevent reocclusion. But there has no study on large sample of argatroban treated restenosis post cranial stenting. This study will test the safety and efficacy of the argatroban on prevent occlusion and restenosis in patients with intracranial and extracranial artery stenting.

Timeline

Start
2010-08
Primary completion
2013-12
Completion
2014-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Argatroban Small molecule 20 mg Intravenous
Background Aspirin Small molecule
Background Clopidogrel Small molecule