drugset / Trial / NCT01164488
A Study of RO5190591 (Danoprevir) in Healthy Volunteers
NaSingle-groupOpen-labelTreatment
Summary
This non-randomized, open-label study will evaluate the interaction of RO5190591(danoprevir)/ritonavir with and without ketoconazole and the safety and tolerability in healthy volunteers. Participants will be administered repeated daily doses of ketoconazole alone, RO5190591/ritonavir, and RO5190591/ritonavir plus ketoconazole. The anticipated time on study treatment is 25 days.
Timeline
- Start
- 2010-07
- Primary completion
- 2010-08
- Completion
- 2010-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketoconazole | Small molecule | — | — |
| Subject | Ritonavir | Other / unclassified | — | — |
| Subject | danoprevir | Small molecule | — | — |
Indications
No indication recorded.