drugset

drugset / Trial / NCT01169467

Cerebral Perfusion Pressure Using Precedex and Other Sedatives

NCT01169467 ↗

Phase 3 Completed 89 enrolled Duke University Hospira, now a wholly owned subsidiary of Pfizer · collab

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to examine the effects of using dexmedetomidine (Precedex) in addition to the current standard-of-care for sedation.

Timeline

Start: 2009-10
Primary completion: 2013-11
Completion: 2013-11

Publications

Background Lazaridis C, DeSantis SM, Smielewski P, Menon DK, Hutchinson P, Pickard JD, Czosnyka M. Patient-specific thresholds of intracranial pressure in severe traumatic brain injury. J Neurosurg. 2014 Apr;120(4):893-900. doi: 10.3171/2014.1.JNS131292. Epub 2014 Feb 7.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexmedetomidine	Other / unclassified	—	—

Indications