drugset / Trial / NCT01170650

Study for Women With Platinum Resistant Ovarian Cancer Evaluating EC145 in Combination With Doxil® (PROCEED)

NCT01170650

Phase 3 Terminated 441 enrolled Endocyte
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to compare progression-free survival (PFS) (based upon investigator assessment using RECIST v1.1) in participants with platinum-resistant ovarian cancer who receive combination therapy with EC145 and pegylated liposomal doxorubicin (EC145+PLD) with that in participants who receive PLD and placebo.

Timeline

Start
2011-04-22
Primary completion
2015-05-31
Completion
2015-09-08

Drugs

EvaluationDrugModalityDoseRoute
Subject EC20 Diagnostic / imaging agent Intravenous
Subject Vintafolide Other / unclassified Intravenous
Background Doxorubicin Other / unclassified 50 mg/m2

Indications