drugset

drugset / Trial / NCT01172002

Leflunomide Versus Azathioprine for Maintenance Therapy of Lupus Nephritis

NCT01172002 ↗

Unknown 200 enrolled RenJi Hospital AnHui ShengLi Hospital · collab Changhai Hospital · collab First Affiliated Hospital of Wenzhou Medical University · collab Qilu Hospital of Shandong University · collab Second Affiliated Hospital, School of Medicine, Zhejiang University · collab Shanghai 10th People's Hospital · collab Shanghai Zhongshan Hospital · collab The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · collab The First Affiliated Hospital of Anhui Medical University · collab The First Affiliated Hospital of Bengbu Medical University · collab The First Affiliated Hospital of Soochow University · collab The First Affiliated Hospital with Nanjing Medical University · collab Zhejiang University · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

Leflunomide versus Azathioprine for Maintenance Therapy of Lupus Nephritis

Timeline

Start: 2010-03
Primary completion: 2018-06
Completion: —

Publications

Fu Q, Wu C, Dai M, Wang S, Xu J, Dai L, Li Z, He L, Zhu X, Sun L, Lu L, Bao C. Leflunomide versus azathioprine for maintenance therapy of lupus nephritis: a prospective, multicentre, randomised trial and long-term follow-up. Ann Rheum Dis. 2022 Nov;81(11):1549-1555. doi: 10.1136/ard-2022-222486. Epub 2022 Jul 4.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Azathioprine	Small molecule	50 mg	Oral
Comparator	Azathioprine	Small molecule	100 mg	Oral
Subject	Leflunomide	Small molecule	20 mg	Oral

Indications