drugset / Trial / NCT01180192

Postpartum Oxygen Inhalation for the Treatment of Postpartum Haemorrhage

NCT01180192

Phase 4 Unknown 450 enrolled Erzincan Military Hospital
RandomizedCrossoverOpen-labelTreatment

Summary

In the aetiology of postpartum uterine atony, hypoxia is considered an important factor although some suggest that peripheral oxygen saturation is not influenced by oxygen inhalation in women during the first and second stages of labor. Enhancing oxygen delivery to myometrium through additional inhaled oxygen may improve uterine contractions. Therefore, it is reasonable to consider that oxygen inhalation may promote myometrial contraction and prevent postpartum haemorrhage (PPH) due to uterine atony. The tendency for the uterus to relax in women encountering respiratory problems immediately after cesarean section under general anaesthesia further strengthened this theory. The aim of this study was to evaluate the effectiveness of oxygen inhalation immediately after vaginal delivery on blood loss. The investigators hypothesized that inhaled oxygen helps to maintain uterine retraction during immediate postpartum period and hence reduces vaginal blood loss.

Timeline

Start
2010-05
Primary completion
2010-05
Completion
2010-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Oxygen Other / unclassified 8 unknown Other

Indications

No indication recorded.