Paracetamol Toxicity in Septic Patients

Summary

The investigators will examine the toxicity of therapeutic doses of paracetamol in patients in severe sepsis. Patients with fever and severe sepsis will be randomized to receive paracetamol or dypirone. The investigators will monitor blood glutathione and liver enzymes to look for potential toxicity.

Timeline

Start

2010-08

Primary completion

2011-08

Completion

2011-08

Drugs

Indications