Antipsychotics and Gene Expression in Soft Tissues

Summary

Schizophrenia is a severe chronic and disabling mental disorder and is associated with a significant reduction in life expectancy. Atypical antipsychotic treatment compliance may be jeopardized because of drug induced weight gain and abnormalities in carbohydrate and lipid metabolism. Aim: to gain data on drug related effects on gene expression and regulation with special regard to glucose metabolism.

Timeline

Start

2010-07

Primary completion

2017-01-01

Completion

2017-01-01

Drugs

Indications