drugset / Trial / NCT01186224
Plerixafor Harvesting And No Chemotherapy for Transplantation of Autologous STem Cells In Cancer (PHANTASTIC)
NaSingle-groupOpen-labelTreatment
Summary
To assess the efficacy and toxicity of plerixafor (AMD 3100) together with granulocyte-colony stimulating factor (G-CSF) for stem cell mobilisation, in patients with myeloma or lymphoma requiring high dose chemotherapy with stem cell rescue.
Timeline
- Start
- 2010-05
- Primary completion
- 2015-06
- Completion
- 2015-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Plerixafor | Small molecule | 160 ug/kg | — |
| Subject | Plerixafor | Small molecule | 240 ug/kg | — |
| Background | Granulocyte colony-stimulating factor | Protein / enzyme biologic | 5 ug/kg | — |
| Background | Granulocyte colony-stimulating factor | Protein / enzyme biologic | 300 ug | — |
| Background | Granulocyte colony-stimulating factor | Protein / enzyme biologic | 480 ug | — |
| Background | Granulocyte colony-stimulating factor | Protein / enzyme biologic | 600 ug | — |
| Background | Granulocyte colony-stimulating factor | Protein / enzyme biologic | 8 mg/kg | — |