drugset / Trial / NCT01187810

Fenretinide in Children With Recurrent/Resistant ALL, AML, and NHL

NCT01187810

Phase 1 Terminated 3 enrolled South Plains Oncology Consortium
NaSingle-groupOpen-labelTreatment

Summary

The purposee of this study is to determine the safety and dosing of Fenretinide when given continuously for 5 days, every 3 weeks, in pediatric patients with recurrent and/or resistant acute lymphoblastic leukemia (ALL), acute myelogenous leukemia (AML), and non-Hodgkin's lymphoma (NHL).

Timeline

Start
2010-08
Primary completion
2018-04
Completion
2018-04

Drugs

EvaluationDrugModalityDoseRoute
Subject fenretinide Small molecule 925 mg/m2 Intravenous
Background Cytarabine Small molecule Intrathecal
Background Methotrexate Small molecule Intrathecal