drugset / Trial / NCT01188889
RAD001 in Patients With Chronic Phase Chronic Myeloid Leukemia w/ Molecular Disease.
NaSingle-groupOpen-labelTreatment
Summary
Patients participating in this study will have a diagnosis of Chronic Myeloid Leukemia. This study will evaluate whether the addition of an investigational drug called RAD001 given together with Imatinib will better target leukemia stem cells, causing them to die. Stem cells are a small population of cells, existing primarily within the bone marrow, and are believed to be responsible for the ongoing risk of disease relapse.
Timeline
- Start
- 2013-09
- Primary completion
- 2016-12
- Completion
- 2017-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Everolimus | Small molecule | 5 mg | Oral |
| Subject | Everolimus | Small molecule | 7.5 mg | Oral |
| Background | Imatinib | Small molecule | 400 mg | — |