drugset / Trial / NCT01198821
Gem-TABS in Unresectable Pancreatic Carcinoma
Phase 1
Completed
8 enrolled
H. Lee Moffitt Cancer Center and Research Institute
Reliable Cancer Therapies · collab
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to: Find out the largest dose of sodium bicarbonate that can be given with gemcitabine. Determine if the combination of sodium bicarbonate and gemcitabine produces better control of pancreatic cancer than gemcitabine alone.
Timeline
- Start
- 2010-08
- Primary completion
- 2011-06
- Completion
- 2011-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | sodium bicarbonate | Diagnostic / imaging agent | 0.3 g/kg | Oral |
| Subject | sodium bicarbonate | Diagnostic / imaging agent | 0.5 g/kg | Oral |
| Subject | sodium bicarbonate | Diagnostic / imaging agent | 1 g/kg | Oral |
| Background | Gemcitabine | Small molecule | 1000 mg/m2 | Intravenous |