drugset / Trial / NCT01202591
Safety and Efficacy of AZD4547 in Combination With Fulvestrant vs. Fulvestrant Alone in ER+ Breast Cancer Patients
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study is to assess the safety and effectiveness of AZD4547 in combination with fulvestrant vs. fulvestrant alone in ER+ breast cancer patients with FGFR1 polysomy (FISH4/5) or gene amplification (FISH 6)
Timeline
- Start
- 2010-12
- Primary completion
- 2014-09
- Completion
- 2014-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fexagratinib | Small molecule | — | Oral |
| Background | Exemestane | Small molecule | — | Oral |
| Background | Fulvestrant | Small molecule | — | Intramuscular |