Drugs / Fulvestrant
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Fulvestrant

Small molecule targets AR, ESR1 via inhibition

Developed for
breast cancer · hormone receptor-positive breast cancer · female breast carcinoma · estrogen-receptor positive breast cancer · Her2-receptor negative breast cancer · breast neoplasm · HER2 positive breast carcinoma · non-small cell lung carcinoma
+51 more · invasive breast carcinoma · ovarian cancer · cancer · metastatic malignant neoplasm · breast carcinoma · endometrial cancer · ovarian carcinoma · progesterone-receptor positive breast cancer · prostate cancer · endometrial carcinoma · metastatic neoplasm · neoplasm · metastatic malignant neoplasm in the brain · prostate carcinoma · soft tissue sarcoma · breast carcinoma by gene expression profile · colorectal cancer · ductal breast carcinoma in situ · endometrial endometrioid adenocarcinoma · endometrium adenocarcinoma · head and neck cancer · head and neck squamous cell carcinoma · hormone-resistant breast carcinoma · invasive lobular breast carcinoma · leiomyosarcoma of the corpus uteri · lung cancer · malignant ovarian serous tumor · McCune-Albright syndrome · metastatic carcinoma · metastatic carcinoma in the bone · metastatic melanoma · ovarian serous adenocarcinoma · ovarian serous tumor · pancreatic ductal adenocarcinoma · pancreatic large cell neuroendocrine carcinoma · pancreatic neuroendocrine tumor · precocious puberty · pulmonary arterial hypertension · salivary gland carcinoma · secondary malignant neoplasm · sex cord-stromal tumor · systemic lupus erythematosus · urothelial carcinoma · uterine carcinoma · uterine corpus adenosarcoma · uterine corpus cancer · uterine corpus endometrial stromal sarcoma · basal-like breast carcinoma · breast lobular carcinoma · invasive ductal breast carcinoma · luminal B breast carcinoma
Investigated by
AstraZeneca · Pfizer · National Cancer Institute (NCI) · Novartis Pharmaceuticals · Eli Lilly and Company · Fudan University
+225 more · Genentech, Inc. · Hoffmann-La Roche · UNICANCER · Dana-Farber Cancer Institute · Jiangsu HengRui Medicine Co., Ltd. · Novartis · ImmunityBio, Inc. · Spanish Breast Cancer Research Group · Sun Yat-sen University · M.D. Anderson Cancer Center · Massachusetts General Hospital · Mayo Clinic · Merck Sharp & Dohme LLC · Alliance for Clinical Trials in Oncology · Bayer · BeOne Medicines · Breast International Group · Celcuity Inc · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Consorzio Oncotech · GBG Forschungs GmbH · Henan Cancer Hospital · Liaoning Cancer Hospital & Institute · Memorial Sloan Kettering Cancer Center · Puma Biotechnology, Inc. · SOLTI Breast Cancer Research Group · SWOG Cancer Research Network · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · United States Department of Defense · Zhejiang Cancer Hospital · Apices Soluciones S.L. · Avenzo Therapeutics, Inc. · Beth Israel Deaconess Medical Center · Brigham and Women's Hospital · Calithera Biosciences, Inc · Chinese Academy of Medical Sciences · City of Hope Medical Center · Clinical Research Technology S.r.l. · Daiichi Sankyo · Dartmouth-Hitchcock Medical Center · ETOP IBCSG Partners Foundation · Effector Therapeutics · Georgetown University · Gilead Sciences · Hunan Cancer Hospital · Institute of Cancer Research, United Kingdom · Kashiv BioSciences, LLC · Korea University Guro Hospital · Lowell General Hospital · MedSIR · National Cancer Institute, France · National Institutes of Health (NIH) · OHSU Knight Cancer Institute · Ohio State University Comprehensive Cancer Center · Roswell Park Cancer Institute · Royal Marsden NHS Foundation Trust · Seoul National University Hospital · Taiho Oncology, Inc. · Tianjin Medical University Cancer Institute and Hospital · Translational Oncology Research International · University of California, Irvine · University of Chicago · University of Colorado, Denver · University of Pittsburgh · University of Ulm · University of Wisconsin, Madison · Washington University School of Medicine · iOMEDICO AG · AMS Advanced Medical Services GmbH · ARCAGY/ GINECO GROUP · Aadi Bioscience, Inc. · Abramson Cancer Center at Penn Medicine · Accelerated Community Oncology Research Network · Adrienne G. Waks · all 231 on the full record

Regulatory milestones approvals, filings & regulatory actions · 15 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansion US (FDA) FULVESTRANT — 2021-05-12 fda.gov ↗
Label expansions (12) US (FDA) FASLODEX — 2003-12-24 – 2020-07-28 fda.gov ↗
Approved EU (EMA) Faslodex — 2004-03-09 europa.eu ↗
Approved US (FDA) FASLODEX — 2002-04-25 fda.gov ↗

Trials 307 · started per year

today
US approved 2002
EU approved 2004
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT05238831 Jan 2023 → May 2026 female breast carcinoma, ovarian carcinoma, pancreatic ductal adenocarcinoma, pancreatic large cell neuroendocrine carcinoma +2 OHSU Knight Cancer Institute Withdrawn No outcome recorded
Phase 152 trials · 2 met primary
Phase 1 NCT07867262 Dec 2026 → Aug 2030 expected breast cancer Genentech, Inc. Not yet recruiting No outcome recorded
Phase 1 NCT07604272 Oct 2026 → Jul 2028 expected hernia, double inguinal Northwestern University Recruiting No outcome recorded
Phase 1 NCT07604571 May 2026 → Jun 2032 expected hormone receptor-positive breast cancer Novartis Pharmaceuticals Recruiting No outcome recorded
Phase 1 NCT07540572 Mar 2026 → Mar 2030 expected castration-resistant prostate carcinoma, colorectal carcinoma, estrogen-receptor positive breast cancer, non-small cell lung carcinoma IDEAYA Biosciences Recruiting No outcome recorded
Phase 1 NCT07226349 Dec 2025 → Nov 2028 expected neoplasm BeOne Medicines Recruiting No outcome recorded
Phase 1 NCT07163481 Oct 2025 → Dec 2026 expected female breast carcinoma Hunan Cancer Hospital Not yet recruiting No outcome recorded
Phase 1 NCT06995482 Aug 2025 → May 2026 overdue — Kashiv BioSciences, LLC Recruiting No outcome recorded
Phase 1 NCT07038369 Jul 2025 → Aug 2028 expected cervical carcinoma, endometrial carcinoma, estrogen-receptor positive breast cancer, fallopian tube cancer +3 Atavistik Bio, Inc Active not recruiting No outcome recorded
Phase 1 NCT06784193 Dec 2024 → May 2027 expected castration-resistant prostate carcinoma, estrogen-receptor positive breast cancer, non-small cell lung carcinoma, progesterone-receptor positive breast cancer Olema Pharmaceuticals, Inc. Recruiting No outcome recorded
Phase 1 NCT06663072 Dec 2024 → Nov 2026 expected pancreatic neuroendocrine tumor University of Chicago Recruiting No outcome recorded
Phase 1/240 trials · 1 missed
Phase 1/2 NCT07861932 Oct 2026 → Sep 2028 expected breast neoplasm KymaThera, Inc. Not yet recruiting No outcome recorded
Phase 1/2 NCT07811232 Sep 2026 → Sep 2030 expected breast neoplasm, endometrium neoplasm, soft tissue sarcoma Advenchen Pharmaceuticals, LLC. Not yet recruiting No outcome recorded
Phase 1/2 NCT07570966 Jun 2026 → Aug 2031 castration-resistant prostate carcinoma, hormone receptor-positive breast cancer Novartis Pharmaceuticals Withdrawn No outcome recorded Stop: Business
Phase 1/2 NCT07389733 Mar 2026 → Dec 2028 expected breast cancer Shandong Suncadia Medicine Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT07235176 Jan 2026 → Nov 2028 expected Her2-receptor negative breast cancer Qilu Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT07288359 Dec 2025 → May 2031 expected castration-resistant prostate carcinoma, hormone receptor-positive breast cancer Novartis Pharmaceuticals Recruiting No outcome recorded
Phase 1/2 NCT06998407 Aug 2025 → Aug 2028 expected hormone receptor-positive breast cancer Avenzo Therapeutics, Inc. Recruiting No outcome recorded
Phase 1/2 NCT06851442 May → Nov 2025 breast cancer Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Terminated No outcome recorded Stop: Business
Phase 1/2 NCT06726148 Apr 2025 → Sep 2028 expected hormone receptor-positive breast cancer, small cell lung carcinoma Novartis Pharmaceuticals Recruiting No outcome recorded
Phase 1/2 NCT06788197 Mar 2025 → Mar 2028 expected breast cancer Henan Cancer Hospital Not yet recruiting No outcome recorded
Phase 2160 trials · 8 met primary · 11 missed
Phase 2 NCT07748208 Oct 2026 → Jun 2029 expected breast cancer, type 2 diabetes mellitus Hoffmann-La Roche Not yet recruiting No outcome recorded
Phase 2 NCT07857226 Sep 2026 → Jun 2028 expected breast cancer Hebei Medical University Fourth Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07340619 May 2026 → Nov 2028 expected metastatic melanoma UNICANCER Not yet recruiting No outcome recorded
Phase 2 NCT07227233 Mar 2026 → Dec 2027 expected breast cancer University of California, San Diego Recruiting No outcome recorded
Phase 2 NCT07498478 Mar 2026 → Jun 2027 expected breast cancer TransThera Sciences (Nanjing), Inc. Recruiting No outcome recorded
Phase 2 NCT07235618 Jan 2026 → Jan 2028 expected breast cancer Sun Yat-sen University Not yet recruiting No outcome recorded
Phase 2 NCT07333937 Dec 2025 → Nov 2027 expected breast cancer Xijing Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07330544 Nov 2025 → Nov 2027 expected breast cancer Zhejiang Cancer Hospital Recruiting No outcome recorded
Phase 2 NCT07179939 Sep 2025 → Dec 2030 expected HER2 positive breast carcinoma Fudan University Not yet recruiting No outcome recorded
Phase 2 NCT07037199 Aug 2025 → Jun 2028 expected breast cancer Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Recruiting No outcome recorded
Show all 160 trials opens the full record — a long page
Phase 2/34 trials
Phase 2/3 NCT06506955 Oct 2024 → Apr 2027 expected metastatic neoplasm Taiho Oncology, Inc. Enrolling by invitation No outcome recorded
Phase 2/3 NCT04753177 Jan 2021 → Jan 2023 — Saint Petersburg State Budgetary Healthcare Institution, City Clinical Oncology Dispensary Unknown No outcome recorded
Phase 2/3 NCT02692755 Sep 2016 → Dec 2019 hormone receptor-positive breast cancer Georgetown University Completed No outcome recorded
Phase 2/3 NCT02116803 May 2014 → Nov 2016 cancer Novartis Pharmaceuticals Completed No outcome recorded
Phase 339 trials · 5 met primary · 7 missed
Phase 3 NCT07802626 Oct 2026 → Oct 2034 expected hormone receptor-positive breast cancer SWOG Cancer Research Network Not yet recruiting No outcome recorded
Phase 3 NCT07683754 Sep 2026 → Jul 2030 expected HER2 positive breast carcinoma, female breast carcinoma, hormone receptor-positive breast cancer Daiichi Sankyo Not yet recruiting No outcome recorded
Phase 3 NCT07062965 Aug 2025 → Jul 2027 expected breast cancer Pfizer Recruiting No outcome recorded
Phase 3 NCT06757634 Jul 2025 → Mar 2029 expected breast cancer Celcuity Inc Recruiting No outcome recorded
Phase 3 NCT06764186 Jan 2025 → Dec 2027 expected breast cancer AstraZeneca Active not recruiting No outcome recorded
Phase 3 NCT06635447 Sep 2024 → Oct 2026 expected breast cancer AstraZeneca Active not recruiting No outcome recorded
Phase 3 NCT06380751 Aug 2024 → Dec 2029 expected breast cancer AstraZeneca Recruiting No outcome recorded
Phase 3 NCT05646862 Jun 2023 → Nov 2026 expected breast cancer Hoffmann-La Roche Recruiting No outcome recorded
Phase 3 NCT05501886 Dec 2022 → Jun 2026 overdue breast cancer Celcuity Inc Active not recruiting Met primary
Phase 3 NCT04851613 Feb 2022 → Oct 2026 expected breast cancer Laekna Limited Active not recruiting No outcome recorded
Phase 47 trials
Phase 4 NCT05631795 Aug 2022 → Jun 2025 breast cancer Novartis Pharmaceuticals Completed No outcome recorded
Phase 4 NCT05362760 Apr 2022 → Apr 2029 expected hormone receptor-positive breast cancer University of Ulm Recruiting No outcome recorded
Phase 4 NCT05191914 Feb → Jul 2022 breast cancer Liaoning Cancer Hospital & Institute Unknown No outcome recorded
Phase 4 NCT04031885 Aug 2019 → Aug 2020 breast cancer Eli Lilly and Company Terminated No outcome recorded Stop: Enrollment
Phase 4 NCT03591549 Aug 2018 → Aug 2021 breast cancer Assiut University Unknown No outcome recorded
Phase 4 NCT03355157 Mar 2018 → Aug 2024 breast cancer GBG Forschungs GmbH Completed No outcome recorded
Phase 4 NCT02447328 May 2015 → May 2016 breast cancer AstraZeneca Completed No outcome recorded
Phase not applicable4 trials
— NCT06856200 Feb → Oct 2025 overdue Her2-receptor negative breast cancer, hormone-resistant breast carcinoma Fudan University Recruiting No outcome recorded
— NCT05295043 Dec 2022 → Jan 2024 Her2-receptor negative breast cancer Tianjin Medical University Cancer Institute and Hospital Unknown No outcome recorded
— NCT05047848 Aug 2021 → Jun 2022 female breast carcinoma Liaoning Cancer Hospital & Institute Unknown No outcome recorded
— NCT00126464 Nov 2004 → ? breast cancer Cedars-Sinai Medical Center Unknown No outcome recorded
Comparator or background therapy210 trials
Phase 0 NCT02913430 Comparator Apr 2018 → Apr 2022 breast cancer Shannon Puhalla Completed No outcome recorded
Phase 1 NCT07358377 Background May 2026 → Apr 2027 expected breast cancer Atridia Pty Ltd. Recruiting No outcome recorded
Phase 1 NCT07480681 Background Mar 2026 → Mar 2028 expected — Shanghai Henlius Biotech Not yet recruiting No outcome recorded
Phase 1 NCT07408089 Background Feb 2026 → Feb 2029 expected breast cancer Boundless Bio, Inc. Recruiting No outcome recorded
Phase 1 NCT07366632 Comparator Jan → May 2026 overdue — Shanghai Best-Link Bioscience, LLC Not yet recruiting No outcome recorded
Show all 210 trials opens the full record — a long page

News releases announcing trial results or a regulatory action · 106

DateIssuerRelease
2026-06-02 Celcuity Inc Results Celcuity’s Gedatolisib Combination Regimens Doubled the Likelihood of Survival without Disease Progression or Death Compared to Alpelisib plus Fulvestrant in the PIK3CA Mutant Cohort of the Pivotal Phase 3 VIKTORIA-1 Trial in Patients with HR+/HER2- Advanced Breast Cancer celcuity.com ↗
Gedatolisib plus fulvestrant and palbociclib (the “gedatolisib-triplet”) reduced the risk of disease progression or death by 50% vs. alpelisib plus fulvestrant (HR=0.50; 95% CI: 0.37–0.68; p<0.0001).
2026-05-18 Biotheryx, Inc. Results Biotheryx Announces Data from its Phase 1 Dose Escalation Study of BTX-9341, a First-in-Class, Potent and Selective CDK4/6 Degrader, for the Treatment of Advanced/Metastatic HR+/HER2- Breast Cancer biotheryx.com ↗
Importantly, BTX-9341 was well tolerated, with participants on treatment for over 12 cycles (48 weeks), including on monotherapy and in combination with fulvestrant.
2026-05-06 Totus Medicines Results Totus Medicines Presents Early Phase 1b Clinical Data Demonstrating 100% Disease Control Rate and Class-Leading Safety for TOS-358 + Fulvestrant Doublet Therapy in HR+/HER2- Breast Cancer at ESMO Breast Cancer Annual Congress 2026 totusmedicines.com ↗
First presentation of combination data demonstrates 100% disease control rate and 89% clinical benefit rate in women, including PAM-experienced patients, with median time on therapy exceeding 24 weeks
2026-05-06 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Regulatory 库莫西利一线治疗乳腺癌获批上市!中国生物制药推动CDK治疗迈入新阶段 cttq.com ↗
5月6日,国家药品监督管理局(NMPA)官网显示,中国生物制药(1177.HK)核心企业正大天晴自主研发的库莫西利胶囊(赛坦欣®)第2个适应症获批上市,联合氟维司群用于激素受体(HR)阳性、人表皮生长因子受体2(HER2)阴性的局部晚期或转移性乳腺癌患者的初始内分泌治疗。
2026-05-01 Celcuity Inc Results Celcuity's Phase 3 VIKTORIA-1 Trial Achieves Primary Endpoint With Clinically Meaningful Improvement in Progression-Free Survival in PIK3CA Mutant Cohort celcuity.com ↗
The primary efficacy analysis of gedatolisib combined with fulvestrant and palbociclib (the “gedatolisib triplet”) demonstrated a statistically significant and clinically meaningful improvement in progression-free survival (“PFS”) compared to alpelisib, a PI3Kα inhibitor, and fulvestrant.
2026-04-27 Relay Therapeutics, Inc. Results Relay Therapeutics Announces Clinical Data for Zovegalisib plus Atirmociclib Triplet Combination Supportive of Further Development in Frontline Metastatic Breast Cancer relaytx.com ↗
2026-04-17 Olema Pharmaceuticals, Inc. Results Olema Oncology Announces Preclinical Data for Palazestrant and OP-3136 at the 2026 AACR Annual Meeting olema.com ↗
Combining OP-3136 with palazestrant or fulvestrant suppresses expression of genes associated with MTORC1 signaling, indicating that targeting KAT6 and ER-alpha can suppress mechanisms of acquired resistance.
2026-04-15 Laekna Limited Results Positive Topline Results | Laekna’s Phase III Clinical Trial of LAE002 (afuresertib) for Breast Cancer Met Primary Endpoint Positive Topline Results | Laekna’s Phase III Clinical Trial of LAE002 (afuresertib) for Breast Cancer Met Primary Endpoint laekna.com ↗
The study met its primary endpoint, LAE002 (afuresertib) plus fulvestrant combination demonstrated a highly statistically significant and clinically meaningful improvement of PFS versus control.
2026-03-16 Relay Therapeutics, Inc. Results Relay Therapeutics Announces Data from Zovegalisib + Fulvestrant at the Phase 3 Dose of 400mg BID Fed at ESMO Targeted Anticancer Therapies Congress 2026 relaytx.com ↗
“As supported by the data presented, the 400mg BID fed regimen maintains robust efficacy with a safety profile consistent with mutant-selective PI3Kα inhibition,” said Don Bergstrom, M.D., Ph.D., President of R&D at Relay Therapeutics.
2026-03-09 Celcuity Inc Results Celcuity Announces Publication of Results from PIK3CA Wild-Type Cohort of Phase 3 VIKTORIA-1 Study of Gedatolisib Regimens in HR+/HER2- Advanced Breast Cancer in Journal of Clinical Oncology celcuity.com ↗
The publication is titled “VIKTORIA-1 Trial of Gedatolisib Plus Fulvestrant With or Without Palbociclib in Hormone Receptor-Positive/HER2-/PIK3CA Wild-Type Advanced Breast Cancer.”
2026-02-12 Laekna Limited Results Nature Communications, February Issue | Afuresertib Plus Fulvestrant Was Well Tolerated and Had Promising Anti-Tumor Activities Against Pretreated, Advanced HR-positive, Her2-negative Breast Cancer Nature Communications, February Issue | Afuresertib Plus Fulvestrant Was Well Tolerated and Had Promising Anti-Tumor Activities Against Pretreated, Advanced HR-positive, Her2-negative Breast Cancer laekna.com ↗
The findings indicate that this combination regimen was well-tolerated and had promising antitumor activities against pretreated, advanced HR-positive, HER2-negative breast cancer.
2026-02-03 Relay Therapeutics, Inc. Regulatory Relay Therapeutics Announces Zovegalisib Granted Breakthrough Therapy Designation by U.S. FDA for PIK3CA-mutant, HR+/HER2- Advanced Breast Cancer relaytx.com ↗
This Breakthrough Therapy designation underscores the FDA’s recognition of the potential of zovegalisib in combination with fulvestrant to meaningfully improve outcomes for these patients, reinforcing the impact of the encouraging clinical evidence we have demonstrated to date.

All press releases naming this drug 117 releases

DateIssuerRelease
Show all 117 releases opens the full record — a long page

Evidence & citations 13 cited values

Every value below carries the sentence it was read from. 521 sources stand behind the page.

FieldValueCited text
Known as Fulvestrant “Patients will be enrolled into the study and assign to receive Palbociclib 125 mg/day orally for 3 weeks followed by 1 week off plus fulvestrant 500 mg intramuscularly on Days...” NCT04318223 ↗
512

“Options include tamoxifen (20 mg daily), aromatase inhibitors (letrozole 2.5 mg daily, anastrozole 1 mg daily, or exemestane 25 mg daily), or fulvestrant (500 mg...” NCT07708194 ↗

“Endocrine therapy is determined by the doctor, including any kind of letrozole, anastrozole, exemestane, fulvestrant, tamoxifen, toremifene, combined with or without drugs or...” NCT03204734 ↗

“Letrozole:2.5mg,q4w or Anastrozole:1mg,q4w or Exemestane:25mg,q4w or Fulvestrant:Patients will receive intramuscular Fulvestrant on day 1 and day 15 of the first cycle and then...” NCT07810088 ↗

“The study is designed to evaluate the safety, tolerability, and pharmacokinetics (PK) of a single dose of Fulvestrant for Injectable Suspension vs. the reference drug,...” NCT03324061 ↗

“Endocrine therapy (physician's choice based on prior administered agent including tamoxifen, exemestane, fulvestrant, anastrozole, or letrozole). Endocrine therapy must be...” NCT03184090 ↗

“This single-arm, phase Ib trial evaluated the antitumor activities and safety of afuresertib (apan AKT inhibitor) plus fulvestrant for previously treated HR-positive,...” PMID 41651834 ↗ Feb 2026

“Cohort A is for patients with HR+/HER2- (hormone receptor positive/human epidermal growth factor receptor 2 negative) advanced breast cancer treated with PM in combination with...” NCT06431243 ↗

“Patients with HR-positive, HER2-negative, locally recurrent or metastatic breast cancer were randomized (2:1) to receive culmerciclib plus fulvestrant or matching placebo plus...” PMID 41413016 ↗ Dec 2025

“Futibatinib 20mg once daily on a 28-day cycle and fulvestrant 500 mg administered intramuscularly (IM) on Days 1 and 15 of Cycle 1, then on Day 1 of Cycle 2 and beyond on a...” NCT04024436 ↗

“We tested this hypothesis in a phase II neoadjuvant trial of anastrozole and fulvestrant combined with gefitinib in postmenopausal women with newly diagnosed ER-positive breast cancer.” PMID 21792626 ↗ Jul 2011

Show 502 more sources

Known as Faslodex “Single-arm study with the primary objective of assessing the efficacy and safety of palbociclib in combination with fulvestrant (Faslodex) in women with HR+, HER2-negative...” NCT04318223 ↗
24

“The study is designed to evaluate the safety, tolerability, and pharmacokinetics (PK) of a single dose of Fulvestrant for Injectable Suspension vs. the reference drug,...” NCT03324061 ↗

“A Randomized, Open-Label Phase II Clinical Trial of Combination Erlotinib (Tarceva®) and Fulvestrant (Faslodex®) Versus Erlotinib (Tarceva®) Alone in Advanced Non-Small Cell...” NCT00100854 ↗

“Reference Product: Faslodex® (Fulvestrant), 5 mL pre-filled syringe containing 250 mg/5 mL of fulvestrant, administered as two 5 mL injections (total 500 mg) via intramuscular...” NCT06995482 ↗

“The main purpose of this research study is to see if adding fulvestrant (Faslodex) to erlotinib (Tarceva) is effective in patients with stage IIIb/IV Non-Small Cell Lung Cancer.” NCT00592007 ↗

“Combined with a background therapy of 500 mg Fulvestrant (Faslodex®) (once a month intramuscular injection, with an additional 500 mg dose given two weeks after the first dose)” NCT03099174 ↗

“Drug: Fulvestrant Participants will receive intramuscular (IM) fulvestrant every 2 weeks during Cycle 1 and then every 4 weeks Other Names: • Faslodex” NCT06757634 ↗

“A Phase II Trial to Evaluate the Combination of ZD1839 (Iressa) and Fulvestrant (Faslodex®) in Patients With Advanced or Metastatic Breast Cancer” NCT00234403 ↗

“Fulvestrant(which also goes by the tradename, Faslodex) was recently approved by the Food and Drug Administration (FDA) to treat breast cancer.” NCT01186796 ↗

“They are being offered voluntary admission to this study to test the effects of a new investigational drug called Fulvestrant (Faslodex).” NCT00183963 ↗

“Compare the Efficacy and Tolerability of Fulvestrant (FASLODEX) 500 mg With Anastrozole (ARIMIDEX) 1 mg as Hormonal Treatment” NCT01602380 ↗

Show 14 more sources

Known as Fulvestrant (Faslodex) “Fulvestrant (Faslodex)” NCT02000596 ↗
Known as Fulvestrant mylan ChEMBL registry synonym — accepted as the source's own label CHEMBL1358 ↗
Known as ICI 182,780 “Faslodex (Long Acting ICI 182,780)” NCT00635713 ↗
1

NCT00417430 ↗

Known as KSHN001034 “Open Label Sequential Dosing Single Ascending Dose of Four Cohort and Multiple Dose of One Cohort Pharmacokinetics Tolerability and Safety of Fulvestrant Injection as Test...” NCT06074757 ↗
Known as NSC #719276 “Combination Fulvestrant (NSC #719276) Plus ZD1839” NCT00057941 ↗
Known as NSC-759879 ChEMBL registry synonym — accepted as the source's own label CHEMBL1358 ↗
Known as ZD-9238 ChEMBL registry synonym — accepted as the source's own label CHEMBL1358 ↗
Action Inhibit “Hormone therapy using fulvestrant may fight cancer by blocking the uptake of estrogen by the tumor cells.” NCT00006903 ↗
Modality Small molecule “the steroidal anti-oestrogen fulvestrant” PMID 23902874 ↗ Jul 2013
Route Intramuscular “Given intramuscularly” NCT00006903 ↗
Target AR “fulvestrant downregulates androgen receptor (AR)” NCT00476645 ↗