drugset / Trial / NCT06663072

Study to Test the Combination of Fulvestrant With Lu-DOTATATE for Advanced Pancreatic Neuroendocrine Tumors

NCT06663072

Phase 1 Recruiting 25 enrolled University of Chicago
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a phase I, open-label study to assess the safety and preliminary efficacy of Fulvestrant in combination with 177Lu-DOTATATE for advanced pNETs.

Timeline

Start
2024-12-13
Primary completion
2026-11
Completion
2026-11

Drugs

EvaluationDrugModalityDoseRoute
Subject 177Lu-DOTATATE Peptide 3700 mbq Intravenous
Subject 177Lu-DOTATATE Peptide 7400 mbq Intravenous
Subject Fulvestrant Small molecule 500 mg Intramuscular