drugset / Trial / NCT02404051
Fulvestrant and EVerolimus Plus EXemestane in Metastatic Breast Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a multi-center, randomized, open-label, parallel group study designed to evaluate efficacy and safety of fulvestrant followed, at progression, by examestane and everolimus versus examestane and everolimus followed, at progression, by fulvestrant in postmenopausal women with HR+ and HER2- LABC or MBC whose disease has progressed to NSAI in the adjuvant or metastatic setting.
Timeline
- Start
- 2015-12
- Primary completion
- 2018-01
- Completion
- 2019-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Everolimus | Small molecule | 10 mg | — |
| Subject | Exemestane | Small molecule | 25 mg | — |
| Subject | Fulvestrant | Small molecule | 500 mg | Intramuscular |