drugset / Trial / NCT02404051

Fulvestrant and EVerolimus Plus EXemestane in Metastatic Breast Cancer

NCT02404051

RandomizedParallel-groupOpen-labelTreatment

Summary

This is a multi-center, randomized, open-label, parallel group study designed to evaluate efficacy and safety of fulvestrant followed, at progression, by examestane and everolimus versus examestane and everolimus followed, at progression, by fulvestrant in postmenopausal women with HR+ and HER2- LABC or MBC whose disease has progressed to NSAI in the adjuvant or metastatic setting.

Timeline

Start
2015-12
Primary completion
2018-01
Completion
2019-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Everolimus Small molecule 10 mg
Subject Exemestane Small molecule 25 mg
Subject Fulvestrant Small molecule 500 mg Intramuscular