drugset / Trial / NCT01211275

Standard Chemotherapy With of Without Axitinib in Malignant Mesothelioma

NCT01211275

Phase 1/2 Completed 32 enrolled The Netherlands Cancer Institute Pfizer · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to investigate the effects of axitinib, a potent angiogenesis inhibitor, on tissue and clinical outcome in combination with chemotherapy given to patients with mesothelioma

Timeline

Start
2009-05-22
Primary completion
2012-11-13
Completion
2013-05-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Axitinib Small molecule 5 mg
Background Cisplatin Other / unclassified 75 mg/m2
Background Pemetrexed Small molecule 500 mg/m2