Selenium in the Treatment of Complicated Lymphatic Malformations

Summary

The investigators propose a pilot trial to obtain preliminary information regarding the safety and response rate of patients with symptomatic lymphatic malformations treated with oral Selenium. Information obtained in this pilot trial will be used to plan future phase 2 clinical trials. Hypotheses: * Selenium will be safe and efficacious in the treatment of adolescents and young adults with symptomatic lymphatic malformations * Disease response will correlate with serum levels of selenium and blood levels of antioxidants essential to selenium metabolism.

Timeline

Start

2010-09

Primary completion

2011-09

Completion

2012-11

Drugs

Indications