Drugs / Selenium
last change Nov 2025 re-read 8 days ago

Selenium

Other / unclassified

Developed for
prostate cancer · COVID-19 · infectious disease with sepsis · male infertility · urinary bladder cancer · acute kidney injury · cardiovascular disorder · cataract
+21 more · central serous chorioretinopathy · Chagas disease · chemotherapy-induced oral mucositis · colorectal adenoma · colorectal cancer · lichen planus, oral · lung cancer · lymphatic malformation · macular degeneration · multiple sclerosis · peripartum cardiomyopathy · precancerous condition · preneoplastic lesion · subarachnoid hemorrhage · trisomy 21 · tuberculosis · adenomatous colon polyp · end stage renal failure · endocrine exophthalmos · endometriosis · ulcerative colitis
Investigated by
National Cancer Institute (NCI) · SWOG Cancer Research Network · Cancer and Leukemia Group B · NCIC Clinical Trials Group · Tehran University of Medical Sciences · University Health Network, Toronto
+60 more · Al-Azhar University · Alcon Research · Arkansas Children's Hospital Research Institute · Augusta University · Beijing Chao Yang Hospital · Beytepe Murat Erdi Eker State Hospital · CHRISTUS Health · Canadian Institutes of Health Research (CIHR) · Cefak KG, Kempten · Centre Hospitalier Universitaire Vaudois · Centre Hospitalier de Meaux · Children's Hospital Los Angeles · Children's Hospital of Michigan · Children's National Research Institute · Conselho Nacional de Desenvolvimento Científico e Tecnológico · Delta University for Science and Technology · ECOG-ACRIN Cancer Research Group · Eastern Cooperative Oncology Group · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · Father Sean O'Sullivan Research Centre · Fresenius Kabi · Harborview Injury Prevention and Research Center · Health Canada · Hector-Stiftung · Heidelberg University · IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy · Institute of Child Health · LILT (Italian league against cancer) · Medical College of Wisconsin · Michael Dean · Ministry of Health, Brazil · Ministry of Health, France · National Center for Complementary and Integrative Health (NCCIH) · National Eye Institute (NEI) · National Institute of Allergy and Infectious Diseases (NIAID) · North Central Cancer Treatment Group · Ondokuz Mayıs University · Oswaldo Cruz Foundation · Penn State University · Pharco Pharmaceuticals · Prince of Songkla University · Roswell Park Cancer Institute · Schwabe-Wenex International Ltd · Seattle Children's Hospital · Shriners Hospitals for Children · Sphinx university · St. Joseph's Health Care London · Tanta University · The Prostate Cancer Research Foundation of Canada · Unity Health Toronto · University Hospital Birmingham · University of Birmingham · University of California, Los Angeles · University of California, San Francisco · University of North Carolina · University of Oklahoma · University of Pennsylvania · University of Pittsburgh · Ursapharm, Saarbrücken · Yale University

Trials 33

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT04005222 May 2014 → Sep 2016 — Beytepe Murat Erdi Eker State Hospital Completed No outcome recorded
Phase 12 trials
Phase 1 NCT01212965 Sep 2010 → Sep 2011 lymphatic malformation Medical College of Wisconsin Terminated No outcome recorded
Phase 1 NCT00217516 Mar 2005 → Feb 2008 prostate cancer Roswell Park Cancer Institute Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT01432873 Jun 2011 → Oct 2012 chemotherapy-induced oral mucositis Tehran University of Medical Sciences Unknown No outcome recorded
Phase 1/2 NCT00010842 Sep 1999 → Dec 2004 multiple sclerosis National Center for Complementary and Integrative Health (NCCIH) Completed No outcome recorded
Phase 27 trials · 2 missed
Phase 2 NCT04869579 Aug → Nov 2021 COVID-19 CHRISTUS Health Unknown No outcome recorded
Phase 2 NCT02421887 Dec 2015 → Jun 2018 male infertility Yale University Completed Missed primary
Phase 2 NCT01554345 Jun 2011 → Aug 2012 acute kidney injury Tehran University of Medical Sciences Unknown No outcome recorded
Phase 2 NCT00844792 Oct 2008 → Dec 2013 prostate cancer University Health Network, Toronto Completed No outcome recorded
Phase 2 NCT00744549 May 2008 → Dec 2013 prostate cancer University Health Network, Toronto Completed No outcome recorded
Phase 2 NCT00963131 Dec 2004 → Dec 2008 central serous chorioretinopathy Prince of Songkla University Completed No outcome recorded
Phase 2 NCT00207844 Jan 2002 → Jan 2005 infectious disease with sepsis Centre Hospitalier de Meaux Completed Missed primary
Phase 313 trials · 7 missed
Phase 3 NCT05614349 Jan 2023 → Apr 2025 overdue COVID-19 Unity Health Toronto Active not recruiting Missed primary
Phase 3 NCT00875173 Oct 2008 → Dec 2016 Chagas disease Oswaldo Cruz Foundation Unknown Missed primary
Phase 3 NCT00706121 Jun 2008 → Oct 2015 colorectal cancer, precancerous condition SWOG Cancer Research Network Completed Missed primary
Phase 3 NCT00395161 Apr 2007 → Nov 2009 infectious disease with sepsis Michael Dean Terminated Missed primary
Phase 3 NCT00553124 Dec 2005 → ? urinary bladder cancer University Hospital Birmingham Unknown No outcome recorded
Phase 3 NCT00553345 Dec 2005 → ? urinary bladder cancer University of Birmingham Unknown No outcome recorded
Phase 3 NCT00784225 Jul 2004 → Nov 2017 cataract, macular degeneration SWOG Cancer Research Network Completed Missed primary
Phase 3 NCT00515736 Jan 2003 → Dec 2005 subarachnoid hemorrhage Centre Hospitalier Universitaire Vaudois Terminated No outcome recorded Stop: Enrollment
Phase 3 NCT00006392 Jul 2001 → May 2011 prostate cancer SWOG Cancer Research Network Completed Missed primary
Phase 3 NCT00008385 Dec 2000 → Jun 2011 lung cancer ECOG-ACRIN Cancer Research Group Completed Missed primary
Phase 44 trials
Phase 4 NCT06362005 May 2024 → Jul 2025 lichen planus, oral Al-Azhar University Completed No outcome recorded
Phase 4 NCT00860379 Jan 2009 → Dec 2019 — Shriners Hospitals for Children Terminated No outcome recorded Stop: Enrollment
Phase 4 NCT00186706 Sep 2005 → Nov 2007 cardiovascular disorder, chronic obstructive pulmonary disease St. Joseph's Health Care London Completed No outcome recorded
Phase 4 NCT00160901 Aug 2003 → Dec 2005 breast cancer Heidelberg University Completed No outcome recorded
Phase not applicable4 trials · 1 missed
— NCT07334197 Dec 2026 → Dec 2029 expected peripartum cardiomyopathy Tanta University Not yet recruiting No outcome recorded
— NCT06042738 Mar → Nov 2021 male infertility Ondokuz Mayıs University Completed No outcome recorded
— NCT04942769 Dec 2019 → Jul 2021 — Beijing Chao Yang Hospital Unknown No outcome recorded
— NCT00378456 — trisomy 21 Institute of Child Health Completed Missed primary
Comparator or background therapy8 trials
Phase 2 NCT02058212 Comparator Mar → Oct 2013 endometriosis Cairo University Completed No outcome recorded
Phase 2/3 NCT06117436 Comparator Oct 2023 → Dec 2024 — Ain Shams University Completed No outcome recorded
Phase 2/3 NCT03476044 Comparator Jun 2018 → Mar 2020 — Assiut University Completed No outcome recorded
Phase 3 NCT04080622 Comparator Oct 2019 → Oct 2023 chemotherapy-induced oral mucositis, disease related to hematopoietic stem cell transplant University Hospital, Angers Completed No outcome recorded
Phase 3 NCT00078897 Comparator Jan 2005 → Jan 2014 adenomatous colon polyp, colorectal cancer, precancerous condition University of Arizona Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 43 sources stand behind the page.

FieldValueCited text
Known as selenium “food supplement containing 2000 mg L-carnitine, 2000 mg fructose, 932 mg acetyl L-carnitine, 225 mg vitamin C, 115 mg citric acid, 50 mg coenzyme Q10, 14 mg zinc, 115 µg...” NCT06042738 ↗
40

“Tablet: Vitamin C, 500 mg; Vitamin D3, 1000 IU; Vitamin E, 400 IU; Folic Acid 1000 mcg; Zinc, 20 mg; Selenium 200 mcg; Lycopene, 10 mg; Capsule: Vitamin D3, 1000 IU,...” NCT02421887 ↗

“The second therapeutic arm investigates a combination antioxidant therapy (selenium 300 µg, zinc 40 mg, lycopene 45 mg and vitamin C 1.5 g), administered for 10 days.” PMID 40754325 ↗ Aug 2025

“Twice a day with meals. Lycopene - 20 mg, Vitamin D3 - 200 IU, Selenium - 100 mcg, Green Tea Extract - 75 mg, Vitamin E - 50 IU” NCT00844792 ↗

“daily supplementation with a combination of alpha-tocopherol, vitamin C, and selenium” NCT00339768 ↗

“daily oral medication consisting of selenium (sodium-selenit 100 microg/d)” NCT00160901 ↗

“tablets composed of 200 mcg selenium \[as l-selenomethionine\]” NCT01437826 ↗

“Lycopene, Vitamin D3, Selenium, Green Tea Extract, Vitamin E” NCT00744549 ↗

“selenium 15 mcg” NCT07758335 ↗

“selenium 40 mg” NCT00963131 ↗

NCT00008385 ↗

Show 30 more sources

Known as Selenium - Laboratoire Aguettant “Selenium - Laboratoire Aguettant” NCT00515736 ↗
Known as sodium selenite “Patients received, for 10 days, selenium as sodium selenite (4,000 microg on the first day, 1,000 microg/day on the nine following days) or matching placebo using continuous...” PMID 17617901 ↗ 2007
Known as sodium-selenit “selenium (sodium-selenit 100 microg/d)” NCT00160901 ↗
Modality Other / unclassified “combination of AOX micronutrient supplements” NCT00515736 ↗
Route Oral “Oral selenium (200 microg/d from L-selenomethionine)” PMID 19066370 ↗ Dec 2008