drugset / Trial / NCT06042738
Investigation of The Effectiveness of Antioxidant Therapy in Oligoasthenoteratozoospermic Infertile Men
RandomizedParallel-groupDouble-blindSupportive care
Summary
Approximately 30% of the factors that cause male infertility are due to idiopathic causes. Increased reactive oxygen species (ROS) due to many known and unknown factors cause male infertility by affecting spermatogenesis and sperm maturation. In this study, the effects of physical activity and antioxidant food supplementation on seminal antioxidant capacity, sperm DNA fragmentation index, sperm chromatin quality and sperm parameters were investigated in infertile cases.
Timeline
- Start
- 2021-03-01
- Primary completion
- 2021-11-01
- Completion
- 2021-11-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetylcarnitine | Small molecule | 932 mg | — |
| Subject | Coenzyme Q10 | Other / unclassified | 50 mg | — |
| Subject | Fructose | Small molecule | 2000 mg | — |
| Subject | L-carnitine | Other / unclassified | 2000 mg | — |
| Subject | Selenium | Other / unclassified | 115 ug | — |
| Subject | Vitamin B12 | Other / unclassified | 3750 ug | — |
| Subject | Vitamin C | Other / unclassified | 225 mg | — |
| Subject | Zinc Sulfate | Unknown | 14 mg | — |
| Subject | citric acid | Unknown | 115 mg | — |
| Subject | folic acid | Other / unclassified | 500 ug | — |