Drugs / citric acid

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) IRRIGATING SOLUTION G IN PLASTIC CONTAINER 1982-06-22 fda.gov

Trials 13 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT07700277 Aug 2026 → Aug 2027 expected intestinal disorder Ottawa Hospital Research Institute Not yet recruiting No outcome recorded
Phase 11 trial
Phase 1 NCT01421160 Jul 2011 → Mar 2012 arthritic joint disease Texas Tech University Health Sciences Center, El Paso Withdrawn No outcome recorded
Phase 2/33 trials
Phase 2/3 NCT05918029 Aug 2024 → Aug 2026 overdue bone resorption disease, chronic kidney disease Albert Einstein College of Medicine Recruiting No outcome recorded
Phase 2/3 NCT04842331 Sep 2021 → Jan 2022 COVID-19, viral respiratory tract infection Thirty Respiratory Limited Withdrawn No outcome recorded
Phase 2/3 NCT01012349 Feb → May 2011 Azidus Brasil Unknown No outcome recorded
Phase 32 trials
Phase 3 NCT04386070 May 2022 → Dec 2026 COVID-19, severe acute respiratory syndrome University of Birmingham Suspended No outcome recorded
Phase 3 NCT01984008 Oct 2013 → Mar 2014 Universal Integrated Corp. Completed No outcome recorded
Phase 42 trials
Phase 4 NCT04161599 Mar 2022 → Jun 2024 Hospital Universitari Vall d'Hebron Research Institute Unknown No outcome recorded
Phase 4 NCT01481714 Nov 2011 → Mar 2012 Infante, Javier Molina, M.D. Unknown No outcome recorded
Phase not applicable4 trials
NCT07708792 Aug → Oct 2026 expected gingival disorder Dijlah University Not yet recruiting No outcome recorded
NCT06042738 Mar → Nov 2021 male infertility Ondokuz Mayıs University Completed No outcome recorded
NCT04033250 Sep 2019 → Sep 2020 Rambam Health Care Campus Unknown No outcome recorded
NCT02359942 Mar 2015 → Dec 2018 Helicobacter pylori infectious disease Seoul National University Bundang Hospital Completed No outcome recorded
Also used as a comparator or background therapy in 3 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT02015260 Comparator Sep 2001 → May 2003 anogenital human papillomavirus infection University of Aberdeen Completed No outcome recorded
Phase 42 trials
Phase 4 NCT03769402 Comparator Jan 2016 → May 2018 periodontal disorder Ain Shams University Completed No outcome recorded
Phase 4 NCT00586131 Comparator Sep 2003 → Apr 2008 end stage renal failure Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 16 sources stand behind the page.

FieldValueCited text
Known as citric acid “food supplement containing 2000 mg L-carnitine, 2000 mg fructose, 932 mg acetyl L-carnitine, 225 mg vitamin C, 115 mg citric acid, 50 mg coenzyme Q10, 14 mg zinc, 115 µg...” NCT06042738
14

“RESP301 is a formulation consisting of three agents already used in clinical practice: mannitol, sodium nitrite and citric acid.” NCT04386070

“RESP301 is a formulation consisting of 3 agents currently used in clinical practice: mannitol, sodium nitrite and citric acid.” NCT04842331

“A) 3% sodium nitrite + 4.5% citric acid creams twice daily” NCT02015260

NCT05918029

NCT04033250

NCT01012349

NCT07700277

NCT07708792

NCT04161599

NCT02359942

NCT01421160

NCT01481714

NCT01984008

NCT03769402

Known as anhydrous citric acid “Drug: Sodium picosulfate, light magnesium oxide, anhydrous citric acid 10 mg/3.5 g/10.97 g Oral” NCT04161599
Known as sodium citrate/citric acid “Arterial pH was varied by changing the daily doses of sodium citrate/citric acid and ammonium chloride.” PMID 19846545 Oct 2009
Route Oral “association Geolab consisting of acetylsalicylic acid, sodium bicarbonate and anhydrous citric acid - oral powder” NCT01012349