drugset / Trial / NCT03769402

The Influence of Citric Acid Bone Surface Etching and Bone Defect Fill on GCF BMP-2 Release Profile

NCT03769402

Phase 4 Completed 20 enrolled Ain Shams University
RandomizedParallel-groupSingle-blindTreatment

Summary

This study evaluates the effect of citric acid on bone surface of infrabony defects when used for 30 seconds at ph 1 and 50% concentration before the application of bovine derived xenograft to fill the defect, Bone Morphogenic protein 2 (BMP-2) marker was evaluated in 5 different days during the first month after surgery and clinical and radiographic parameters were reassessed after 6 months

Timeline

Start
2016-01-01
Primary completion
2018-05-01
Completion
2018-11-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator citric acid Unknown 50 %

Indications