drugset / Trial / NCT05266794

A Novel Role of Alpha Lipoic Acid in Comparison With Selenium in Mitochondrial Resuscitation and miRNA-126 Expression in Hemodialysis Patients

NCT05266794

Phase 4 Completed 68 enrolled Ain Shams University
RandomizedParallel-groupOpen-labelPrevention

Summary

An Open labeled, Paralled, Randomized, Prospective, study was conducted on 60 patients who were randomized into 3 groups, 22, 20 and 18 patients in Control, Selenium and, Thiotacid groups respectively. Serum levels of ROS, CoQ10, and miRNA-126 were assessed at base line and after three months for all patients.

Timeline

Start
2019-01-22
Primary completion
2019-04-23
Completion
2019-04-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Selenium Other / unclassified 200 ug
Comparator alpha-lipoic acid Small molecule 600 mg