Impact of Cilostazol Versus Cilostazol and Selenium Combination on the Healing of Diabetic Foot Ulcer Patients

Phase 2/3 Completed 206 enrolled Ain Shams University

RandomizedParallel-groupOpen-labelTreatment

Summary

The growing incidence of DM can lead to the increased prevalence of diabetic foot complications, which have become a serious medical, social, and economic concern of global importance. this study aims to find a novel intervention that improve wound healing in diabetic foot ulcer to improve patients' quality of life, reduce amputation rate, and reduce the mortality rate among diabetic foot ulcer patients

Timeline

Start: 2023-10-19
Primary completion: 2024-12-30
Completion: 2025-01-30

Publications

Eliwa HE, Wakeel LME, Mahfouz AA, Sayed R. Impact of Cilostazol versus Cilostazol and Selenium Combination on The Healing of Diabetic Foot Ulcer Patients: A Randomized Controlled Trial. Diabetol Metab Syndr. 2026 Jan 6;18(1):36. doi: 10.1186/s13098-025-02053-4.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Cilostazol	Small molecule	100 mg	Oral
Comparator	Selenium	Other / unclassified	200 ug	Oral

Indications

No indication recorded.