drugset / Trial / NCT01214057
Total Intravenous Anesthesia (TIVA) vs. Inhaled Anesthesia for Endoscopic Sinus Surgery.
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to compare total intravenous anesthesia to inhaled anesthesia in endoscopic sinus surgery for chronic sinusitis. The investigators will compare bleeding during surgery, duration of surgery, blood flow to the nose and other parameters. The investigators hypothesize that total intravenous anesthesia decreases bleeding and improves the view during surgery.
Timeline
- Start
- 2010-05
- Primary completion
- 2012-10
- Completion
- 2012-10
Outcome
Outcome not reported
Stopped (Enrollment): “the study was terminated for patient recruitment difficulty and interim power analysis”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Propofol | Small molecule | 100 ug/kg | Intravenous |
| Subject | Propofol | Small molecule | 150 ug/kg | Intravenous |
| Subject | Propofol and Remifentanyl | Unknown | 0.2 ug/kg | Intravenous |
| Comparator | Sevoflurane | Other / unclassified | 1 % | Inhaled |
| Comparator | Sevoflurane | Other / unclassified | 3 % | Inhaled |
| Comparator | Sevoflurane and Remifentanyl | Unknown | 0.2 ug/kg | Intravenous |