drugset / Trial / NCT01214057

Total Intravenous Anesthesia (TIVA) vs. Inhaled Anesthesia for Endoscopic Sinus Surgery.

NCT01214057 ↗

RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to compare total intravenous anesthesia to inhaled anesthesia in endoscopic sinus surgery for chronic sinusitis. The investigators will compare bleeding during surgery, duration of surgery, blood flow to the nose and other parameters. The investigators hypothesize that total intravenous anesthesia decreases bleeding and improves the view during surgery.

Timeline

Start
2010-05
Primary completion
2012-10
Completion
2012-10

Outcome

Outcome not reported

Stopped (Enrollment): “the study was terminated for patient recruitment difficulty and interim power analysis”

Drugs

EvaluationDrugModalityDoseRoute
Subject Propofol Small molecule 100 ug/kg Intravenous
Subject Propofol Small molecule 150 ug/kg Intravenous
Subject Propofol and Remifentanyl Unknown 0.2 ug/kg Intravenous
Comparator Sevoflurane Other / unclassified 1 % Inhaled
Comparator Sevoflurane Other / unclassified 3 % Inhaled
Comparator Sevoflurane and Remifentanyl Unknown 0.2 ug/kg Intravenous