drugset / Trial / NCT01214083
N-acetylcysteine Plus Naltrexone for the Treatment of Alcohol Dependence
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to determine whether: (1) the combination of N-acetylcysteine + high-dose naltrexone (150 mg) works better than high-dose naltrexone (150 mg) alone in reducing alcohol drinking; and (2) high-dose naltrexone (150 mg) alone works better than low-dose naltrexone (50 mg) alone in reducing alcohol drinking.
Timeline
- Start
- 2010-10-15
- Primary completion
- 2015-09-30
- Completion
- 2016-10-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | N-acetylcysteine | Small molecule | — | — |
| Subject | Naltrexone | Small molecule | 50 mg | — |
| Subject | Naltrexone | Small molecule | 150 mg | — |