drugset / Trial / NCT01216007
A Pilot Study to Investigate Plasma Bupivacaine Concentrations in Children Receiving Total Intravenous Anaesthesia and Caudal Analgesia
RandomizedParallel-groupSingle-blindDiagnostic
Summary
The objective of this pilot study is to compare plasma \[bupivacaine\] between two groups of paediatric patients under general anaesthesia who will all receive regional caudal anaesthesia with bupivacaine: group 1 will receive TIVA and group 2 will receive a volatile anaesthetic.
Timeline
- Start
- 2010-10
- Primary completion
- 2012-10
- Completion
- 2012-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | 200 ug/kg | Intravenous |
| Comparator | Propofol | Small molecule | 400 ug/kg | Intravenous |
| Comparator | Sevoflurane | Other / unclassified | 5 % | Inhaled |
| Comparator | Sevoflurane | Other / unclassified | 8 % | Inhaled |
Indications
No indication recorded.