drugset / Trial / NCT01220154

Study of Intraperitoneal Carboplatin With IV Paclitaxel and Bevacizumab in Untreated Ovarian Cancer

NCT01220154 ↗

Phase 1 Completed 9 enrolled David O'Malley Genentech, Inc. · collab
NaSingle-groupOpen-labelTreatment

Summary

Phase I study to evaluate intraperitoneal carboplatin along with weekly intravenous paclitaxel and bevacizumab in order to establish a tolerable dose and define the toxicity of this regimen in previously untreated patients with advanced ovarian carcinoma.

Timeline

Start
2011-04-28
Primary completion
2023-07-17
Completion
2023-07-17

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 15 mg/kg Intravenous
Subject Carboplatin Small molecule — Other
Subject Paclitaxel Small molecule 60 mg/m2 Intravenous
Subject Paclitaxel Small molecule 80 mg/m2 Intravenous