drugset / Trial / NCT01224847
Intravitreal Injection Anesthesia - Comparison of Different Topical Agents
Completed
92 enrolled
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
RandomizedFactorialDouble-blindTreatment
Summary
Patients with neovascular age-related macular degeneration (AMD) scheduled to receive intravitreal (IVT) Ranibizumab injection will be randomized to receive one of three topical anesthetics: (1) tetracaine drop (gtt) + lidocaine pledget to the injection site for 10 seconds (2) tetracaine gtt alone and (3) cocaine gtt alone. A questionnaire will be conducted immediately after and 15 minutes after the injection, to assess for pain.
Timeline
- Start
- 2009-10
- Primary completion
- 2009-11
- Completion
- 2009-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cocaine | Small molecule | 1 unknown | Topical |
| Comparator | Lidocaine | Other / unclassified | — | Topical |
| Comparator | tetracaine | Other / unclassified | 1 unknown | Topical |