drugset / Trial / NCT01229774

Use of Etoricoxib Compared to Diclofenac in the Perioperative Treatment of Patients After Total Hip Arthroplasty

NCT01229774

RandomizedParallel-groupTriple-blindTreatment

Summary

The primary aim of this study is to test if etoricoxib decreases the perioperative blood loss compared to diclofenac. Secondary questions to be explored are: * Does etoricoxib prevent Heterotopic ossification after Total Hip Arthroplasty as well as diclofenac ? * Do diclofenac and etoricoxib both reduce pain at rest and on movements? * Does etoricoxib compared to diclofenac reduce the amount of rescue medication (Oxycodon)? * Does etoricoxib improve gastrointestinal tolerability compared to diclofenac?

Timeline

Start
2011-02
Primary completion
2014-08
Completion
2014-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Diclofenac Other / unclassified 75 mg
Subject Etoricoxib Small molecule 90 mg

Indications