drugset / Trial / NCT01229774
Use of Etoricoxib Compared to Diclofenac in the Perioperative Treatment of Patients After Total Hip Arthroplasty
RandomizedParallel-groupTriple-blindTreatment
Summary
The primary aim of this study is to test if etoricoxib decreases the perioperative blood loss compared to diclofenac. Secondary questions to be explored are: * Does etoricoxib prevent Heterotopic ossification after Total Hip Arthroplasty as well as diclofenac ? * Do diclofenac and etoricoxib both reduce pain at rest and on movements? * Does etoricoxib compared to diclofenac reduce the amount of rescue medication (Oxycodon)? * Does etoricoxib improve gastrointestinal tolerability compared to diclofenac?
Timeline
- Start
- 2011-02
- Primary completion
- 2014-08
- Completion
- 2014-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Diclofenac | Other / unclassified | 75 mg | — |
| Subject | Etoricoxib | Small molecule | 90 mg | — |