drugset / Trial / NCT01231074

Reducing Antipsychotic-Induced Weight Gain in Children With Metformin

NCT01231074 ↗

Phase 1 Completed 96 enrolled Nationwide Children's Hospital
Non-randomizedParallel-groupOpen-labelTreatment

Summary

Recent but limited short term studies have shown that Metformin can slow down weight gain in obese children and in children with psychotropic-induced weight gain, two distinct pediatric populations that are at risk for obesity related co-morbid conditions. The purpose of this study is to conduct a long term prospective pilot cohort study to investigate the use of Metformin to prevent or decrease weight gain in two cohorts of children: 1) children with psychotropic induced weight gain on Metformin and 2) children with BMI above the 95th percentile on Metformin. Both study populations will be enrolled in a lifestyle weight management program

Timeline

Start
2010-02
Primary completion
2012-02
Completion
2013-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 1000 mg —

Indications