drugset / Trial / NCT01232829

Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas Cancer

NCT01232829

Phase 2 Completed 18 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase II trial is studying how well RO4929097 (gamma-secretase/Notch signalling pathway inhibitor RO4929097) works in treating patients with previously treated metastatic pancreatic cancer. RO4929097 may stop the growth of tumor cells by blocking some enzymes needed for cell growth.

Timeline

Start
2010-10
Primary completion
2012-07
Completion
2014-05

Drugs

EvaluationDrugModalityDoseRoute
Subject RG4733 Small molecule Oral