drugset / Trial / NCT01234038

Safety and Tolerability Study of ISIS EIF4E Rx in Combination With Carboplatin and Paclitaxel

NCT01234038

Phase 1/2 Completed 116 enrolled Ionis Pharmaceuticals, Inc.
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to examine the overall survival of patients with Stage IV non-small cell lung cancer (NSCLC) treated with ISIS EIF4E Rx in combination with carboplatin and paclitaxel.

Timeline

Start
2010-11
Primary completion
2012-10
Completion
2013-01

Drugs

EvaluationDrugModalityDoseRoute
Subject ISIS EIF4E Rx Unknown 800 mg Intravenous
Subject ISIS EIF4E Rx Unknown 1000 mg Intravenous
Background Carboplatin Small molecule 6 unknown Intravenous
Background Paclitaxel Small molecule 200 mg/m2 Intravenous