drugset / Trial / NCT01234116

Post-Exposure Prophylaxis in Health Care Workers

NCT01234116

RandomizedParallel-groupOpen-labelTreatment

Summary

Objective: The objective of this study is to determine the safety and tolerability of Post-exposure Prophylaxis (PEP) with a regimen of Truvada + Kaletra among health care workers (HCWs) at Henry Ford Hospital. Hypothesis: Raltegravir is safe and better tolerated compared with Kaletra, each in combination with Truvada, as assessed by review of completion rates of PEP and also review of completed safety data.

Timeline

Start
2011-02
Primary completion
2013-05
Completion
2013-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Raltegravir Other / unclassified 400 mg
Comparator Ritonavir Other / unclassified
Comparator emtricitabine/tenofovir disoproxil fumarate Unknown