drugset / Trial / NCT01234116
Post-Exposure Prophylaxis in Health Care Workers
RandomizedParallel-groupOpen-labelTreatment
Summary
Objective: The objective of this study is to determine the safety and tolerability of Post-exposure Prophylaxis (PEP) with a regimen of Truvada + Kaletra among health care workers (HCWs) at Henry Ford Hospital. Hypothesis: Raltegravir is safe and better tolerated compared with Kaletra, each in combination with Truvada, as assessed by review of completion rates of PEP and also review of completed safety data.
Timeline
- Start
- 2011-02
- Primary completion
- 2013-05
- Completion
- 2013-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Raltegravir | Other / unclassified | 400 mg | — |
| Comparator | Ritonavir | Other / unclassified | — | — |
| Comparator | emtricitabine/tenofovir disoproxil fumarate | Unknown | — | — |