drugset / Trial / NCT01251146
A Randomized Controlled Study to Assess the Effects of Bisoprolol and Atenolol on Resting Heart Rate and Sympathetic Nervous System's Activity in Subjects With Essential Hypertension
Phase 4
Completed
177 enrolled
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a Phase 4, prospective, multi-centric and randomized controlled study to compare the effects of bisoprolol and atenolol on resting heart rate (RHR) and sympathetic nervous system's (SNS) activity in subjects with essential hypertension.
Timeline
- Start
- 2010-11
- Primary completion
- 2012-02
- Completion
- 2012-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atenolol | Other / unclassified | 100 mg | — |
| Subject | Bisoprolol | Other / unclassified | 10 mg | — |