drugset / Trial / NCT01251393
Cocaine/Crack and Reduction of Compulsion With Biperiden
Phase 3
Completed
111 enrolled
Federal University of São Paulo
Nacional Conseling of Scientific Development and Technology · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
Considering the effects of the cholinergic system on the drug reward and self-administration mechanisms, acetylcholine (Ach) may play an important role on cocaine dependence process. Then the present study aims to evaluate biperiden efficacy (a cholinergic antagonist) in attenuate compulsion, one o the main symptoms of the drug dependence.
Timeline
- Start
- 2011-05
- Primary completion
- 2011-12
- Completion
- 2012-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Biperiden | Small molecule | 6 mg | — |