Drugs / Biperiden
Biperiden
also known as
Akineton · Akineton ret · Akinophyl · Biperiden hcl · BIPERIDEN HYDROCHLORIDE · Biperiden Lactate · Biperidene · Biperideni hydrochloridum · +7 more
Small molecule targets CHRM1 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | AKINETON | — | 1959-09-08 | fda.gov ↗ |
Trials 6
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT00495092 | Jan 2005 → Dec 2009 | cocaine dependence | Hospital Universitari Vall d'Hebron Research Institute | Completed | No outcome recorded |
| Phase 34 trials · 1 missed | ||||||
| Phase 3 | NCT04945213 | Jan 2023 → Dec 2026 expected | post-traumatic epilepsy, traumatic brain injury | Hospital Sirio-Libanes | Recruiting | No outcome recorded |
| Phase 3 | NCT01048138 | Jan 2018 → Dec 2022 | traumatic brain injury | Federal University of São Paulo | Terminated | Missed primary Stop: Enrollment |
| Phase 3 | NCT02374567 | Jan 2015 → Jun 2017 | anxiety disorder, dementia, depressive disorder, schizophrenia +1 | Hannover Medical School | Terminated | No outcome recorded |
| Phase 3 | NCT01251393 | May → Dec 2011 | cocaine dependence | Federal University of São Paulo | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT00495183 | Jan 2009 → Jul 2010 | cocaine dependence | Hospital Universitari Vall d'Hebron Research Institute | Unknown | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 4 | NCT02078336 Comparator | Dec 2013 → Jul 2025 overdue | — | Universitaire Ziekenhuizen KU Leuven | Active not recruiting | No outcome recorded |
Evidence & citations 20 cited values
Every value below carries the sentence it was read from. 8 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Biperiden | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00495092 ↗ |
| Known as | Akineton | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02078336 ↗ |
| Known as | Akineton ret | ChEMBL registry synonym — accepted as the source's own label CHEMBL1101 ↗ |
| Known as | Akinophyl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1101 ↗ |
| Known as | Biperiden hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1101 ↗ |
| Known as | BIPERIDEN HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1101 ↗ |
| Known as | Biperiden Lactate | “Drug: Biperiden Lactate” NCT01048138 ↗ |
| Known as | Biperidene | ChEMBL registry synonym — accepted as the source's own label CHEMBL1101 ↗ |
| Known as | Biperideni hydrochloridum | ChEMBL registry synonym — accepted as the source's own label CHEMBL1101 ↗ |
| Known as | Biperideno | ChEMBL registry synonym — accepted as the source's own label CHEMBL1101 ↗ |
| Known as | Biperidenum | ChEMBL registry synonym — accepted as the source's own label CHEMBL1101 ↗ |
| Known as | KL 373 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1101 ↗ |
| Known as | NSC-170950 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1101 ↗ |
| Known as | NSC-759145 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1101 ↗ |
| Known as | NSC-84989 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1101 ↗ |
| Known as | Tasmolin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1101 ↗ |
| Action | Inhibit | “Biperiden is a cholinergic antagonist, acting in the muscarinic receptor” NCT01048138 ↗1“Muscarinic acetylcholine receptor M1 antagonist” CHEMBL1101 ↗ |
| Modality | Small molecule | — CHEMBL1101 ↗ |
| Route | Oral | “Biperiden 2-4 mg/d p.o.” NCT00495092 ↗ |
| Target | CHRM1 | “Muscarinic acetylcholine receptor M1 antagonist” CHEMBL1101 ↗ |