drugset / Trial / NCT01254604

Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002)

NCT01254604

Phase 3 Completed 190 enrolled Merck Sharp & Dohme LLC
RandomizedParallel-groupDouble-blindTreatment

Summary

This study will test the hypothesis that preservative-free tafluprost (MK-2452) is non-inferior to preservative-free timolol maleate with respect to the diurnal intraocular pressure (IOP) change from baseline after 4 weeks of therapy in participants with open-angle glaucoma or ocular hypertension.

Timeline

Start
2011-12-01
Primary completion
2013-05-09
Completion
2013-05-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Tafluprost Other / unclassified 0.0015 %
Comparator Timolol Other / unclassified 0.5 %