Anti-Platelet Drugs and Brain-derived Neurotrophic Factor (BDNF) in Human Serum and Plasma

Unknown 25 enrolled University of Rostock

NaSingle-groupOpen-labelBasic science

Summary

The impact of anti-platelet drugs on the concentrations of Brain-derived neurotrophic factor (BDNF) in human plasma and serum is unknown. It is the aim of this study to investigate the impact of a single dose of Aspirin (500 mg) or Clopdigrel (600 mg) on the concentrations of Brain-derived neurotrophic factor (BDNF) in plasma and serum of healthy volunteers.

Timeline

Start: 2010-07
Primary completion: 2011-02
Completion: 2011-03

Publications

Background Lommatzsch M, Zingler D, Schuhbaeck K, Schloetcke K, Zingler C, Schuff-Werner P, Virchow JC. The impact of age, weight and gender on BDNF levels in human platelets and plasma. Neurobiol Aging. 2005 Jan;26(1):115-23. doi: 10.1016/j.neurobiolaging.2004.03.002.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Aspirin	Small molecule	500 mg	—
Subject	Clopidogrel	Small molecule	600 mg	—

Indications

No indication recorded.