drugset / Trial / NCT01269346

Eribulin With Trastuzumab as First-line Therapy for Locally Recurrent or Metastatic HER2 Positive Breast Cancer

NCT01269346

Phase 2 Completed 52 enrolled Eisai Inc.
NaSingle-groupOpen-labelTreatment

Summary

This is a multicenter phase 2 study designed to evaluate the safety and efficacy of eribulin mesylate in combination with trastuzumab as first line treatment in female subjects with locally recurrent or metastatic human epidermal growth factor receptor (HER2) positive breast cancer.

Timeline

Start
2010-12
Primary completion
2013-03
Completion
2016-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Eribulin Small molecule 1.4 mg/m2 Intravenous
Background Trastuzumab Monoclonal antibody 6 mg/kg Intravenous