drugset / Trial / NCT01269996
JanUmet Before Insulin Lantus In Eastern Population Evaluation Program (JUBILEE) In Type 2 Diabetic Patients
RandomizedParallel-groupOpen-labelTreatment
Summary
To evaluate the efficacy and safety of a new treatment regimen of metformin plus sitagliptin (Janumet) followed by a long-acting basal insulin (Lantus) treatment compared to the usual treatment regimen of metformin followed by sulfonylurea and intermediate-acting basal insulin in Type 2 Diabetes Mellitus patients.
Timeline
- Start
- 2011-05
- Primary completion
- 2014-07
- Completion
- 2015-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Gliclazide | Small molecule | — | — |
| Comparator | Insulin | Protein / enzyme biologic | — | Other |
| Comparator | Sitagliptin | Small molecule | 50 mg | Oral |
| Comparator | insulin glargine | Protein / enzyme biologic | — | Other |
| Comparator | Metformin | Small molecule | 500 mg | Oral |
| Comparator | Metformin | Small molecule | 1000 mg | Oral |