drugset / Trial / NCT01270802
Effects of Switching Efavirenz to Raltegravir on Vascular Function and Bone Markers in HIV-infected Patients
RandomizedParallel-groupOpen-labelTreatment
Summary
Efavirenz, a commonly used HIV medication, may cause worsening vascular function and bone problems. The purpose of this study is to determine if switching efavirenz to raltegravir, a newer HIV medication, will improve vascular function and tests of bone health.
Timeline
- Start
- 2011-04
- Primary completion
- 2012-10
- Completion
- 2013-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Raltegravir | Other / unclassified | 400 mg | Oral |
| Comparator | Tenofovir/emtricitabine/efavirenz | Unknown | — | — |
| Background | Tenofovir/emtricitabine | Unknown | — | — |