drugset / Trial / NCT01270802

Effects of Switching Efavirenz to Raltegravir on Vascular Function and Bone Markers in HIV-infected Patients

NCT01270802

RandomizedParallel-groupOpen-labelTreatment

Summary

Efavirenz, a commonly used HIV medication, may cause worsening vascular function and bone problems. The purpose of this study is to determine if switching efavirenz to raltegravir, a newer HIV medication, will improve vascular function and tests of bone health.

Timeline

Start
2011-04
Primary completion
2012-10
Completion
2013-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Raltegravir Other / unclassified 400 mg Oral
Comparator Tenofovir/emtricitabine/efavirenz Unknown
Background Tenofovir/emtricitabine Unknown