drugset / Trial / NCT01272141
A Study of Lapatinib in Combination With Everolimus in Patients With Advanced, Triple Negative Breast Cancer
NaSingle-groupOpen-labelTreatment
Summary
The patient is being asked to join this clinical research study to find out if lapatinib, an agent that targets a protein, called epidermal growth factor receptor (EGFR) on the surface of cancer cells in combination with everolimus, an agent that targets a protein in the cancer cell, called mammalian target of rapamycin (mTOR) is effective in metastatic triple negative breast cancers that are no longer controlled by standard chemotherapy.
Timeline
- Start
- 2010-12
- Primary completion
- 2013-01
- Completion
- 2014-01
Outcome
Outcome not reported
Stopped (Enrollment): “Slow accrual, Funding stopped”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Everolimus | Small molecule | 5 mg | Oral |
| Subject | Lapatinib | Small molecule | 1250 mg | Oral |