drugset / Trial / NCT01272141

A Study of Lapatinib in Combination With Everolimus in Patients With Advanced, Triple Negative Breast Cancer

NCT01272141 ↗

Phase 2 Terminated 5 enrolled Emory University
NaSingle-groupOpen-labelTreatment

Summary

The patient is being asked to join this clinical research study to find out if lapatinib, an agent that targets a protein, called epidermal growth factor receptor (EGFR) on the surface of cancer cells in combination with everolimus, an agent that targets a protein in the cancer cell, called mammalian target of rapamycin (mTOR) is effective in metastatic triple negative breast cancers that are no longer controlled by standard chemotherapy.

Timeline

Start
2010-12
Primary completion
2013-01
Completion
2014-01

Outcome

Outcome not reported

Stopped (Enrollment): “Slow accrual, Funding stopped”

Drugs

EvaluationDrugModalityDoseRoute
Subject Everolimus Small molecule 5 mg Oral
Subject Lapatinib Small molecule 1250 mg Oral

Indications