The Use of Bupivacaine and Ropivacaine for Sciatic Nerve Block

Phase 4 Completed 142 enrolled Northwestern University

RandomizedParallel-groupDouble-blindSupportive care

Summary

The duration of motor block for infragluteal parabiceps sciatic nerve block following total knee replacement may vary between 12-36 hrs depending on the amount of local anesthetic given.

Timeline

Start: 2010-11
Primary completion: 2012-08
Completion: —

Publications

Nader A, Kendall MC, De Oliveira GS Jr, Puri L, Tureanu L, Brodskaia A, Asher Y, Parimi V, McCarthy RJ. A dose-ranging study of 0.5% bupivacaine or ropivacaine on the success and duration of the ultrasound-guided, nerve-stimulator-assisted sciatic nerve block: a double-blind, randomized clinical trial. Reg Anesth Pain Med. 2013 Nov-Dec;38(6):492-502. doi: 10.1097/AAP.0b013e3182a4bddf.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Bupivacaine	Other / unclassified	0.5 %	Other
Comparator	Ropivacaine	Other / unclassified	0.5 %	Other

Indications

No indication recorded.