drugset / Trial / NCT01281787
PREvention of Atrial Fibrillation in patientS Undergoing thorAcic surGEry for Lung Cancer
RandomizedParallel-groupOpen-labelPrevention
Summary
The aim of this study is to assess whether prophylactic treatment with metoprolol or losartan is able to reduce the incidence of atrial fibrillation (AF) in patients undergoing thoracic surgery for lung cancer, showing elevated plasma levels in NT probrain natriuretic peptide (NT-proBNP), measured in the perioperative period.
Timeline
- Start
- 2008-04
- Primary completion
- 2013-06
- Completion
- 2013-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Losartan | Other / unclassified | 50 mg | — |
| Comparator | Metoprolol | Other / unclassified | 100 mg | — |