drugset / Trial / NCT01288131
Study of Anti-r-HuEpo Associated Pure Red Cell Aplasia (PRCA) Treatment
RandomizedParallel-groupOpen-labelTreatment
Summary
Recombinant human erythropoietin (r-HuEpo) has been used to treat renal anemia and improve morbidity and mortality in chronic kidney disease. Subcutaneous use of r-HuEpo causes immunogenicity and develops anti-r-HuEpo associated pure red cell aplasia (PRCA). The treatment of anti-r-HuEpo associated pure red cell aplasia is controversial. The investigators aim to evaluate the treatment for anti-r-HuEpo associated pure red cell aplasia in this study.
Timeline
- Start
- 2009-01
- Primary completion
- 2012-01
- Completion
- 2012-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cyclophosphamide | Other / unclassified | 100 mg | — |
| Comparator | Cyclosporine | Peptide | 100 mg | — |
| Comparator | Mycophenolate Mofetil | Small molecule | 750 mg | — |
| Comparator | Prednisolone | Other / unclassified | 1 mg/kg | — |