drugset / Trial / NCT01288131

Study of Anti-r-HuEpo Associated Pure Red Cell Aplasia (PRCA) Treatment

NCT01288131

Phase 3 Terminated 8 enrolled Chulalongkorn University
RandomizedParallel-groupOpen-labelTreatment

Summary

Recombinant human erythropoietin (r-HuEpo) has been used to treat renal anemia and improve morbidity and mortality in chronic kidney disease. Subcutaneous use of r-HuEpo causes immunogenicity and develops anti-r-HuEpo associated pure red cell aplasia (PRCA). The treatment of anti-r-HuEpo associated pure red cell aplasia is controversial. The investigators aim to evaluate the treatment for anti-r-HuEpo associated pure red cell aplasia in this study.

Timeline

Start
2009-01
Primary completion
2012-01
Completion
2012-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cyclophosphamide Other / unclassified 100 mg
Comparator Cyclosporine Peptide 100 mg
Comparator Mycophenolate Mofetil Small molecule 750 mg
Comparator Prednisolone Other / unclassified 1 mg/kg

Indications