drugset / Trial / NCT01294462
Study to Assess Safety and Efficacy of Ticagrelor (AZD6140) Versus Clopidogrel in Asian/Japanese Patients With Non-ST or ST Elevation Acute Coronary Syndromes (ACS)
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of the study is to assess the efficacy (prevention of vascular events) and safety (especially bleedings) of Ticagrelor (AZD6140) compared with Clopidogrel, both given on top of low dose aspirin, in Asian/Japanese patients with acute coronary syndrome and a planned percutaneous coronary intervention (PCI).
Timeline
- Start
- 2011-02
- Primary completion
- 2012-07
- Completion
- 2012-07
Outcome
Results reported · no primary-endpoint met/missed verdict (typical of a dose-finding / safety study)
registry No P-value provided since the objective was not to perform formal statistical comparison. NCT01294462 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Clopidogrel | Small molecule | 75 mg | Oral |
| Subject | Ticagrelor | Small molecule | 90 mg | Oral |
| Background | Aspirin | Small molecule | — | — |